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P450-BM3-Catalyzed Sulfoxidation versus Hydroxylation: A Common or Two Different Catalytically Active Species?

[Image: see text] While the mechanism of the P450-catalyzed oxidative hydroxylation of organic compounds has been studied in detail for many years, less is known about sulfoxidation. Depending upon the structure of the respective substrate, heme-Fe=O (Cpd I), heme–Fe(III)–OOH (Cpd 0), and heme–Fe(II...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Wang, Jian-bo, Huang, Qun, Peng, Wei, Wu, Peng, Yu, Da, Chen, Bo, Wang, Binju, Reetz, Manfred T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307895/
https://ncbi.nlm.nih.gov/pubmed/31927987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b13061
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