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Optogenetic Retinal Gene Therapy with the Light Gated GPCR Vertebrate Rhodopsin

In retinal disease, despite the loss of light sensitivity as photoreceptors die, many retinal interneurons survive in a physiologically and metabolically functional state for long periods. This provides an opportunity for treatment by genetically adding a light sensitive function to these cells. Opt...

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Detalles Bibliográficos
Publicado en:Methods Mol Biol
Main Authors: Gaub, Benjamin M., Berry, Michael H., Visel, Meike, Holt, Amy, Isacoff, Ehud Y., Flannery, John G.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307607/
https://ncbi.nlm.nih.gov/pubmed/29188513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7522-8_12
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