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Restoration of high-sensitivity and adapting vision with a cone opsin

Inherited and age-related retinal degenerative diseases cause progressive loss of rod and cone photoreceptors, leading to blindness, but spare downstream retinal neurons, which can be targeted for optogenetic therapy. However, optogenetic approaches have been limited by either low light sensitivity...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Berry, Michael H., Holt, Amy, Salari, Autoosa, Veit, Julia, Visel, Meike, Levitz, Joshua, Aghi, Krisha, Gaub, Benjamin M., Sivyer, Benjamin, Flannery, John G., Isacoff, Ehud Y.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420663/
https://ncbi.nlm.nih.gov/pubmed/30874546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09124-x
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