Restoration of visual function by expression of a light-gated mammalian ion channel in retinal ganglion cells or ON-bipolar cells

Most inherited forms of blindness are caused by mutations that lead to photoreceptor cell death but spare second- and third-order retinal neurons. Expression of the light-gated excitatory mammalian ion channel light-gated ionotropic glutamate receptor (LiGluR) in retinal ganglion cells (RGCs) of the...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Gaub, Benjamin M., Berry, Michael H., Holt, Amy E., Reiner, Andreas, Kienzler, Michael A., Dolgova, Natalia, Nikonov, Sergei, Aguirre, Gustavo D., Beltran, William A., Flannery, John G., Isacoff, Ehud Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2014
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280620/
https://ncbi.nlm.nih.gov/pubmed/25489083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414162111
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