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Lineage tracing meets single-cell omics: opportunities and challenges

A fundamental goal of developmental and stem cell biology is to map the developmental history (ontogeny) of differentiated cell types. Recent advances in high-throughput single-cell sequencing technologies have enabled the construction of comprehensive transcriptional atlases of adult tissues and of...

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Bibliographic Details
Published in:Nat Rev Genet
Main Authors: Wagner, Daniel E., Klein, Allon M.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307462/
https://ncbi.nlm.nih.gov/pubmed/32235876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41576-020-0223-2
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