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Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain

The lineage relationships among the hundreds of cell types generated during development are difficult to reconstruct. A recent method, GESTALT, used CRISPR-Cas9 barcode editing for large-scale lineage tracing, but was restricted to early development and did not identify cell types. Here we present s...

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Podrobná bibliografie
Vydáno v:Nat Biotechnol
Hlavní autoři: Raj, Bushra, Wagner, Daniel E., McKenna, Aaron, Pandey, Shristi, Klein, Allon M., Shendure, Jay, Gagnon, James A., Schier, Alexander F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938111/
https://ncbi.nlm.nih.gov/pubmed/29608178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.4103
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