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Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo

High-throughput mapping of cellular differentiation hierarchies from single-cell data promises to empower systematic interrogations of vertebrate development and disease. Here, we applied single-cell RNA sequencing to >92,000 cells from zebrafish embryos during the first day of development. Using...

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Détails bibliographiques
Publié dans:Science
Auteurs principaux: Wagner, Daniel E., Weinreb, Caleb, Collins, Zach M., Briggs, James A., Megason, Sean G., Klein, Allon M.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6083445/
https://ncbi.nlm.nih.gov/pubmed/29700229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar4362
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