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Human sirtuins are differentially sensitive to inhibition by nitrosating agents and other cysteine oxidants
Sirtuins (e.g. human Sirt1–7) catalyze the removal of acyl groups from lysine residues in proteins in an NAD(+)-dependent manner, and loss of sirtuin deacylase activity correlates with the development of aging-related diseases. Although multiple reports suggest that sirtuin activity is regulated by...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7307208/ https://ncbi.nlm.nih.gov/pubmed/32371394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011988 |
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