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N-Glycans on EGF domain-specific O-GlcNAc transferase (EOGT) facilitate EOGT maturation and peripheral endoplasmic reticulum localization

Epidermal growth factor (EGF) domain-specific O-GlcNAc transferase (EOGT) is an endoplasmic reticulum (ER)-resident protein that modifies EGF repeats of Notch receptors and thereby regulates Delta-like ligand-mediated Notch signaling. Several EOGT mutations that may affect putative N-glycosylation c...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Alam, Sayad Md. Didarul, Tsukamoto, Yohei, Ogawa, Mitsutaka, Senoo, Yuya, Ikeda, Kazutaka, Tashima, Yuko, Takeuchi, Hideyuki, Okajima, Tetsuya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307186/
https://ncbi.nlm.nih.gov/pubmed/32376684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012280
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