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Specialization for Cell-Free or Cell-to-Cell Spread of BAC-Cloned Human Cytomegalovirus Strains Is Determined by Factors beyond the UL128-131 and RL13 Loci

It is widely held that clinical isolates of human cytomegalovirus (HCMV) are highly cell associated, and mutations affecting the UL128-131 and RL13 loci that arise in culture lead to the appearance of a cell-free spread phenotype. The bacterial artificial chromosome (BAC) clone Merlin (ME) expresses...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Schultz, Eric P., Lanchy, Jean-Marc, Day, Le Zhang, Yu, Qin, Peterson, Christopher, Preece, Jessica, Ryckman, Brent J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307150/
https://ncbi.nlm.nih.gov/pubmed/32321807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00034-20
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