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Depletion interactions modulate the binding between disordered proteins in crowded environments

Intrinsically disordered proteins (IDPs) abound in cellular regulation. Their interactions are often transitory and highly sensitive to salt concentration and posttranslational modifications. However, little is known about the effect of macromolecular crowding on the interactions of IDPs with their...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zosel, Franziska, Soranno, Andrea, Buholzer, Karin J., Nettels, Daniel, Schuler, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306994/
https://ncbi.nlm.nih.gov/pubmed/32487732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1921617117
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