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Transition path times of coupled folding and binding reveal the formation of an encounter complex

The association of biomolecules is the elementary event of communication in biology. Most mechanistic information of how the interactions between binding partners form or break is, however, hidden in the transition paths, the very short parts of the molecular trajectories from the encounter of the t...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Sturzenegger, Flurin, Zosel, Franziska, Holmstrom, Erik D., Buholzer, Karin J., Makarov, Dmitrii E., Nettels, Daniel, Schuler, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226497/
https://ncbi.nlm.nih.gov/pubmed/30413694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07043-x
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