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ADAMTS‐5: A difficult teenager turning 20
A Disintegrin And Metalloproteinase with ThromboSpondin motif (ADAMTS)‐5 was identified in 1999 as one of the enzymes responsible for cleaving aggrecan, the major proteoglycan in articular cartilage. Studies in vitro, ex vivo and in vivo have validated ADAMTS‐5 as a target in osteoarthritis (OA), a...
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| Publicado no: | Int J Exp Pathol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7306899/ https://ncbi.nlm.nih.gov/pubmed/32219922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iep.12344 |
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