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ADAMTS‐5: A difficult teenager turning 20

A Disintegrin And Metalloproteinase with ThromboSpondin motif (ADAMTS)‐5 was identified in 1999 as one of the enzymes responsible for cleaving aggrecan, the major proteoglycan in articular cartilage. Studies in vitro, ex vivo and in vivo have validated ADAMTS‐5 as a target in osteoarthritis (OA), a...

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Detalles Bibliográficos
Publicado en:Int J Exp Pathol
Autor Principal: Santamaria, Salvatore
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306899/
https://ncbi.nlm.nih.gov/pubmed/32219922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iep.12344
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