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A Novel Physiologically Based Model of Creatinine Renal Disposition to Integrate Current Knowledge of Systems Parameters and Clinical Observations

Creatinine is the most common clinical biomarker of renal function. As a substrate for renal transporters, its secretion is susceptible to inhibition by drugs, resulting in transient increase in serum creatinine and false impression of damage to kidney. Novel physiologically based models for creatin...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:CPT Pharmacometrics Syst Pharmacol
Main Authors: Scotcher, Daniel, Arya, Vikram, Yang, Xinning, Zhao, Ping, Zhang, Lei, Huang, Shiew‐Mei, Rostami‐Hodjegan, Amin, Galetin, Aleksandra
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306622/
https://ncbi.nlm.nih.gov/pubmed/32441889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12509
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