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Hybrid Insulin Peptides Are Recognized by Human T Cells in the Context of DRB1*04:01
T cells isolated from the pancreatic infiltrates of nonobese diabetic mice have been shown to recognize epitopes formed by the covalent cross-linking of proinsulin and secretory granule peptides. Formation of such hybrid insulin peptides (HIPs) was confirmed through mass spectrometry, and responses...
Kaydedildi:
| Yayımlandı: | Diabetes |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Diabetes Association
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7306133/ https://ncbi.nlm.nih.gov/pubmed/32291282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0620 |
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