Sex-specific role for the long non-coding RNA LINC00473 in depression

Depression is a common disorder that affects women at twice the rate of men. Here we report that long non-coding RNAs (lncRNAs), a recently discovered class of regulatory transcripts, represent about one-third of the differentially expressed genes in the brains of depressed humans, and display compl...

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Pubblicato in:Neuron
Autori principali: Issler, Orna, van der Zee, Yentl Y., Ramakrishnan, Aarthi, Wang, Junshi, Tan, Chunfeng, Loh, Yong-Hwee E., Purushothaman, Immanuel, Walker, Deena M., Lorsch, Zachary S., Hamilton, Peter J., Peña, Catherine J., Flaherty, Erin, Hartley, Brigham J., Torres-Berrío, Angélica, Parise, Eric M., Kronman, Hope, Duffy, Julia E., Estill, Molly S., Calipari, Erin S., Labonté, Benoit, Neve, Rachael L., Tamminga, Carol A., Brennand, Kristen J., Dong, Yan, Shen, Li, Nestler, Eric J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305959/
https://ncbi.nlm.nih.gov/pubmed/32304628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2020.03.023
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