H3K79me2 dynamics in medium spiny neurons mediate long-term behavioral and cell type-specific molecular effects of early life stress

Animals susceptible to chronic social defeat stress (CSDS) exhibit depression-related behaviors, and show aberrant transcription across several limbic brain regions. The nucleus accumbens (NAc) in particular shows unique susceptible versus resilient phenotypes at the transcriptional, neuroanatomical...

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Udgivet i:Nat Neurosci
Main Authors: Kronman, Hope, Torres-Berrío, Angélica, Sidoli, Simone, Issler, Orna, Godino, Arthur, Ramakrishnan, Aarthi, Mews, Philipp, Lardner, Casey K., Parise, Eric M., Walker, Deena M., van der Zee, Yentl, Browne, Caleb J., Boyce, Brittany F., Neve, Rachael, Garcia, Benjamin A., Shen, Li, Peña, Catherine J., Nestler, Eric J.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8216773/
https://ncbi.nlm.nih.gov/pubmed/33723435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-021-00814-8
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