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Human TRA2A determines influenza A virus host adaptation by regulating viral mRNA splicing
Several avian influenza A viruses (IAVs) have adapted to mammalian species, including humans. To date, the mechanisms enabling these host shifts remain incompletely understood. Here, we show that a host factor, human TRA2A (huTRA2A), inhibits avian IAV replication, but benefits human IAV replication...
שמור ב:
| הוצא לאור ב: | Sci Adv |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Association for the Advancement of Science
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7304988/ https://ncbi.nlm.nih.gov/pubmed/32596447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz5764 |
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