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Transition State Force Field for the Asymmetric Redox Relay Heck Reaction

A transition state force field (TSFF) was developed using the quantum-guided molecular mechanics (Q2MM) method to describe the stereodetermining migratory insertion step of the enantioselective redox-relay Heck reaction for a range of multisubstituted alkenes. We show that the TSFF is highly predict...

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Publicat a:J Am Chem Soc
Autors principals: Rosales, Anthony R., Ross, Sean P., Helquist, Paul, Norrby, Per-Ola, Sigman, Matthew S., Wiest, Olaf
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304536/
https://ncbi.nlm.nih.gov/pubmed/32249569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c01979
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