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Allelic heterogeneity of Proteus syndrome

Proteus syndrome is a mosaic disorder that can cause progressive postnatal overgrowth of nearly any organ or tissue. To date, Proteus syndrome has been exclusively associated with the mosaic c.49G > A p.(Glu17Lys) pathogenic variant in AKT1, a variant that is also present in many cancers. Here we...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cold Spring Harb Mol Case Stud
Hauptverfasser: Buser, Anna, Lindhurst, Marjorie J., Kondolf, Hannah C., Yourick, Miranda R., Keppler-Noreuil, Kim M., Sapp, Julie C., Biesecker, Leslie G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304363/
https://ncbi.nlm.nih.gov/pubmed/32327430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a005181
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