Platinum-Triggered Bond-Cleavage of Pentynoyl Amide and N-Propargyl Handles for Drug-Activation

[Image: see text] The ability to create ways to control drug activation at specific tissues while sparing healthy tissues remains a major challenge. The administration of exogenous target-specific triggers offers the potential for traceless release of active drugs on tumor sites from antibody–drug c...

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Bibliografski detalji
Izdano u:J Am Chem Soc
Glavni autori: Oliveira, Bruno L., Stenton, Benjamin J., Unnikrishnan, V. B., de Almeida, Cátia Rebelo, Conde, João, Negrão, Magda, Schneider, Felipe S. S., Cordeiro, Carlos, Ferreira, Miguel Godinho, Caramori, Giovanni F., Domingos, Josiel B., Fior, Rita, Bernardes, Gonçalo J. L.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2020
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304066/
https://ncbi.nlm.nih.gov/pubmed/32456416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c01622
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