Reduced uptake of [11C]‐ABP688, a PET tracer for metabolic glutamate receptor 5 in hippocampus and amygdala in Alzheimer’s dementia

INTRODUCTION: Metabotropic glutamate receptors play a critical role in the pathogenesis of Alzheimer's disease due to their involvement in processes of memory formation, neuroplasticity, and synaptotoxity. The objective of the current study was to study mGluR5 availability measured by [(11)C]‐A...

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Detalles Bibliográficos
Publicado en:Brain Behav
Main Authors: Treyer, Valerie, Gietl, Anton F., Suliman, Husam, Gruber, Esmeralda, Meyer, Rafael, Buchmann, Andreas, Johayem, Anass, Unschuld, Paul G., Nitsch, Roger M., Buck, Alfred, Ametamey, Simon M., Hock, Christoph
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303388/
https://ncbi.nlm.nih.gov/pubmed/32304284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.1632
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