Piperlongumine Acts as an Immunosuppressant by Exerting Prooxidative Effects in Human T Cells Resulting in Diminished T(H)17 but Enhanced T(reg) Differentiation

Piperlongumine (PL), a natural small molecule derived from the Piper longum Linn plant, has received growing interest as a prooxidative drug with promising anticancer properties. Yet, the influence of PL on primary human T cells remained elusive. Knowledge of this is of crucial importance, however,...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Liang, Jie, Ziegler, Jacqueline D., Jahraus, Beate, Orlik, Christian, Blatnik, Renata, Blank, Norbert, Niesler, Beate, Wabnitz, Guido, Ruppert, Thomas, Hübner, Katrin, Balta, Emre, Samstag, Yvonne
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303365/
https://ncbi.nlm.nih.gov/pubmed/32595640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01172
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