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The pro-oxidative drug WF-10 inhibits serial killing by primary human cytotoxic T-cells
Cytotoxic T-cells (CTLs) play an important role in many immune-mediated inflammatory diseases. Targeting cytotoxicity of CTLs would allow to interfere with immune-mediated tissue destruction. Here we demonstrate that WF-10, a pro-oxidative compound, inhibits CTL-mediated cytotoxicity. WF-10 did not...
Shranjeno v:
| izdano v: | Cell Death Discov |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4979520/ https://ncbi.nlm.nih.gov/pubmed/27551545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2016.57 |
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