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Comparison of the toxicokinetics of the convulsants picrotoxinin and tetramethylenedisulfotetramine (TETS) in mice
Acute intoxication with picrotoxin or the rodenticide tetramethylenedisulfotetramine (TETS) can cause seizures that rapidly progress to status epilepticus and death. Both compounds inhibit γ-aminobutyric acid type-A (GABA(A)) receptors with similar potency. However, TETS is approximately 100 × more...
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| Publicado no: | Arch Toxicol |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7303059/ https://ncbi.nlm.nih.gov/pubmed/32239239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02728-z |
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