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Development of tetramethylenedisulfotetramine (TETS) hapten library: synthesis, electrophysiological studies and immune response in rabbits

There is a need for fast detection methods for the banned rodenticide tetramethylenedisulfotetramine (TETS), a highly potent blocker of the γ-aminobutyric acid (GABA(A)) receptors. General synthetic approach toward two groups of analogues was developed. Screening of the resulting library of compound...

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Publicat a:Chemistry
Autors principals: Barnych, Bogdan, Vasylieva, Natalia, Joseph, Tom, Hulsizer, Susan, Nguyen, Hai M., Cajka, Tomas, Pessah, Isaac, Wulff, Heike, Gee, Shirley J., Hammock, Bruce D.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808876/
https://ncbi.nlm.nih.gov/pubmed/28411375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201700783
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