Opioid system modulation with buprenorphine/samidorphan combination for major depressive disorder: two randomized controlled studies

The endogenous opioid system is thought to play an important role in the regulation of mood. Buprenorphine/samidorphan (BUP/SAM) combination is an investigational opioid system modulator for adjunctive treatment of major depressive disorder (MDD). To confirm results from early studies, we report the...

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Veröffentlicht in:Mol Psychiatry
Hauptverfasser: Fava, Maurizio, Thase, Michael E., Trivedi, Madhukar H., Ehrich, Elliot, Martin, William F., Memisoglu, Asli, Nangia, Narinder, Stanford, Arielle D., Yu, Miao, Pathak, Sanjeev
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303008/
https://ncbi.nlm.nih.gov/pubmed/30374191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0284-1
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