Buprenorphine/samidorphan combination for the adjunctive treatment of major depressive disorder: results of a phase III clinical trial (FORWARD-3)

BACKGROUND: The endogenous opioid system is a fundamental regulator of mood in humans. Previously reported clinical trials have demonstrated the efficacy of the investigational agent buprenorphine/samidorphan (BUP/SAM) combination, an opioid-system modulator, for the adjunctive treatment of major de...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neuropsychiatr Dis Treat
Hauptverfasser: Zajecka, John M, Stanford, Arielle D, Memisoglu, Asli, Martin, William F, Pathak, Sanjeev
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2019
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459143/
https://ncbi.nlm.nih.gov/pubmed/31040679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S199245
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