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Adjunctive Lanicemine (AZD6765) in Patients with Major Depressive Disorder and History of Inadequate Response to Antidepressants: A Randomized, Placebo-Controlled Study

The objective of this study was to investigate the efficacy and safety of adjunctive lanicemine (NMDA channel blocker) in the treatment of major depressive disorder (MDD) over 12 weeks. This phase IIb, randomized, parallel-arm, double-blind, placebo-controlled study was conducted at 49 centers in fo...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Sanacora, Gerard, Johnson, Michael R, Khan, Arif, Atkinson, Sarah D, Riesenberg, Robert R, Schronen, Juan P, Burke, Michael A, Zajecka, John M, Barra, Luis, Su, Hong-Lin, Posener, Joel A, Bui, Khanh H, Quirk, Michael C, Piser, Timothy M, Mathew, Sanjay J, Pathak, Sanjeev
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312066/
https://ncbi.nlm.nih.gov/pubmed/27681442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2016.224
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