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Evaluation of Opioid Modulation in Major Depressive Disorder

Although opioids have known antidepressant activity, their use in major depressive disorder (MDD) has been greatly limited by risk of abuse and addiction. Our aim was to determine whether opioid modulation achieved through a combination of a μ-opioid partial agonist, buprenorphine (BUP), and a poten...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Ehrich, Elliot, Turncliff, Ryan, Du, Yangchun, Leigh-Pemberton, Richard, Fernandez, Emilio, Jones, Reese, Fava, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397403/
https://ncbi.nlm.nih.gov/pubmed/25518754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.330
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