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Evaluation of Opioid Modulation in Major Depressive Disorder

Although opioids have known antidepressant activity, their use in major depressive disorder (MDD) has been greatly limited by risk of abuse and addiction. Our aim was to determine whether opioid modulation achieved through a combination of a μ-opioid partial agonist, buprenorphine (BUP), and a poten...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neuropsychopharmacology
Hauptverfasser: Ehrich, Elliot, Turncliff, Ryan, Du, Yangchun, Leigh-Pemberton, Richard, Fernandez, Emilio, Jones, Reese, Fava, Maurizio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397403/
https://ncbi.nlm.nih.gov/pubmed/25518754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.330
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