Dissociation of TRIF bias and adjuvanticity

Toll-like receptors (TLRs), a family of “pattern recognition receptors,” bind microbial and host-derived molecules, leading to intracellular signaling and proinflammatory gene expression. TLR4 is unique in that ligand-mediated activation requires the co-receptor myeloid differentiation 2 (MD2) to in...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Richard, Katharina, Perkins, Darren J., Harberts, Erin M., Song, Yang, Gopalakrishnan, Archana, Shirey, Kari Ann, Lai, Wendy, Vlk, Alexandra, Mahurkar, Anup, Nallar, Shreeram, Hawkins, Lynn D., Ernst, Robert K., Vogel, Stefanie N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302928/
https://ncbi.nlm.nih.gov/pubmed/32389496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2020.04.042
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