Landscape and Selection of Vaccine Epitopes in SARS-CoV-2

There is an urgent need for a vaccine with efficacy against SARS-CoV-2. We hypothesize that peptide vaccines containing epitope regions optimized for concurrent B cell, CD4(+) T cell, and CD8(+) T cell stimulation would drive both humoral and cellular immunity with high specificity, potentially avoi...

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izdano v:bioRxiv
Main Authors: Smith, Christof C., Entwistle, Sarah, Willis, Caryn, Vensko, Steven, Beck, Wolfgang, Garness, Jason, Sambade, Maria, Routh, Eric, Olsen, Kelly, Kodysh, Julia, O’Donnell, Timothy, Haber, Carsten, Heiss, Kirsten, Stadler, Volker, Garrison, Erik, Grant, Oliver C., Woods, Robert J., Heise, Mark, Vincent, Benjamin G., Rubinsteyn, Alex
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302209/
https://ncbi.nlm.nih.gov/pubmed/32577654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.04.135004
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