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Landscape and Selection of Vaccine Epitopes in SARS-CoV-2

There is an urgent need for a vaccine with efficacy against SARS-CoV-2. We hypothesize that peptide vaccines containing epitope regions optimized for concurrent B cell, CD4(+) T cell, and CD8(+) T cell stimulation would drive both humoral and cellular immunity with high specificity, potentially avoi...

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Pubblicato in:bioRxiv
Autori principali: Smith, Christof C., Entwistle, Sarah, Willis, Caryn, Vensko, Steven, Beck, Wolfgang, Garness, Jason, Sambade, Maria, Routh, Eric, Olsen, Kelly, Kodysh, Julia, O’Donnell, Timothy, Haber, Carsten, Heiss, Kirsten, Stadler, Volker, Garrison, Erik, Grant, Oliver C., Woods, Robert J., Heise, Mark, Vincent, Benjamin G., Rubinsteyn, Alex
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302209/
https://ncbi.nlm.nih.gov/pubmed/32577654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.04.135004
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