Landscape and selection of vaccine epitopes in SARS-CoV-2

BACKGROUND: Early in the pandemic, we designed a SARS-CoV-2 peptide vaccine containing epitope regions optimized for concurrent B cell, CD4(+) T cell, and CD8(+) T cell stimulation. The rationale for this design was to drive both humoral and cellular immunity with high specificity while avoiding und...

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Bibliografische gegevens
Gepubliceerd in:Genome Med
Hoofdauteurs: Smith, Christof C., Olsen, Kelly S., Gentry, Kaylee M., Sambade, Maria, Beck, Wolfgang, Garness, Jason, Entwistle, Sarah, Willis, Caryn, Vensko, Steven, Woods, Allison, Fini, Misha, Carpenter, Brandon, Routh, Eric, Kodysh, Julia, O’Donnell, Timothy, Haber, Carsten, Heiss, Kirsten, Stadler, Volker, Garrison, Erik, Sandor, Adam M., Ting, Jenny P. Y., Weiss, Jared, Krajewski, Krzysztof, Grant, Oliver C., Woods, Robert J., Heise, Mark, Vincent, Benjamin G., Rubinsteyn, Alex
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2021
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201469/
https://ncbi.nlm.nih.gov/pubmed/34127050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00910-1
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