Landscape and selection of vaccine epitopes in SARS-CoV-2

BACKGROUND: Early in the pandemic, we designed a SARS-CoV-2 peptide vaccine containing epitope regions optimized for concurrent B cell, CD4(+) T cell, and CD8(+) T cell stimulation. The rationale for this design was to drive both humoral and cellular immunity with high specificity while avoiding und...

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Dades bibliogràfiques
Publicat a:Genome Med
Autors principals: Smith, Christof C., Olsen, Kelly S., Gentry, Kaylee M., Sambade, Maria, Beck, Wolfgang, Garness, Jason, Entwistle, Sarah, Willis, Caryn, Vensko, Steven, Woods, Allison, Fini, Misha, Carpenter, Brandon, Routh, Eric, Kodysh, Julia, O’Donnell, Timothy, Haber, Carsten, Heiss, Kirsten, Stadler, Volker, Garrison, Erik, Sandor, Adam M., Ting, Jenny P. Y., Weiss, Jared, Krajewski, Krzysztof, Grant, Oliver C., Woods, Robert J., Heise, Mark, Vincent, Benjamin G., Rubinsteyn, Alex
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201469/
https://ncbi.nlm.nih.gov/pubmed/34127050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00910-1
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