Landscape and selection of vaccine epitopes in SARS-CoV-2

BACKGROUND: Early in the pandemic, we designed a SARS-CoV-2 peptide vaccine containing epitope regions optimized for concurrent B cell, CD4(+) T cell, and CD8(+) T cell stimulation. The rationale for this design was to drive both humoral and cellular immunity with high specificity while avoiding und...

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Vydáno v:Genome Med
Hlavní autoři: Smith, Christof C., Olsen, Kelly S., Gentry, Kaylee M., Sambade, Maria, Beck, Wolfgang, Garness, Jason, Entwistle, Sarah, Willis, Caryn, Vensko, Steven, Woods, Allison, Fini, Misha, Carpenter, Brandon, Routh, Eric, Kodysh, Julia, O’Donnell, Timothy, Haber, Carsten, Heiss, Kirsten, Stadler, Volker, Garrison, Erik, Sandor, Adam M., Ting, Jenny P. Y., Weiss, Jared, Krajewski, Krzysztof, Grant, Oliver C., Woods, Robert J., Heise, Mark, Vincent, Benjamin G., Rubinsteyn, Alex
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201469/
https://ncbi.nlm.nih.gov/pubmed/34127050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00910-1
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