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Machine-learning prediction of tumor antigen immunogenicity in the selection of therapeutic epitopes

Current tumor neoantigen calling algorithms primarily rely on epitope/MHC binding affinity predictions to rank and select for potential epitope targets. These algorithms do not predict for epitope immunogenicity using approaches modeled from tumor-specific antigen data. Here, we describe peptide-int...

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Bibliografische gegevens
Gepubliceerd in:Cancer Immunol Res
Hoofdauteurs: Smith, Christof C., Chai, Shengjie, Washington, Amber R., Lee, Samuel J., Landoni, Elisa, Field, Kevin, Garness, Jason, Bixby, Lisa M., Selitsky, Sara R., Parker, Joel S., Savoldo, Barbara, Serody, Jonathan S., Vincent, Benjamin G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774822/
https://ncbi.nlm.nih.gov/pubmed/31515258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-19-0155
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