Microbiota epitope similarity either dampens or enhances the immunogenicity of disease-associated antigenic epitopes

The microbiome influences adaptive immunity and molecular mimicry influences T cell reactivity. Here, we evaluated whether the sequence similarity of various antigens to the microbiota dampens or increases immunogenicity of T cell epitopes. Sets of epitopes and control sequences derived from 38 anti...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Carrasco Pro, Sebastian, Lindestam Arlehamn, Cecilia S., Dhanda, Sandeep K., Carpenter, Chelsea, Lindvall, Mikaela, Faruqi, Ali A., Santee, Clark A., Renz, Harald, Sidney, John, Peters, Bjoern, Sette, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937769/
https://ncbi.nlm.nih.gov/pubmed/29734356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196551
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados