Deriving stratified effects from joint models investigating gene-environment interactions

BACKGROUND: Models including an interaction term and performing a joint test of SNP and/or interaction effect are often used to discover Gene-Environment (GxE) interactions. When the environmental exposure is a binary variable, analyses from exposure-stratified models which consist of estimating gen...

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Publicado en:BMC Bioinformatics
Autores principales: Laville, Vincent, Majarian, Timothy, de Vries, Paul S., Bentley, Amy R., Feitosa, Mary F., Sung, Yun J., Rao, D. C., Manning, Alisa, Aschard, Hugues
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302007/
https://ncbi.nlm.nih.gov/pubmed/32552674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03569-4
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