Liver-Specific siRNA-Mediated Stat3 or C3 Knockdown Improves the Outcome of Experimental Autoimmune Myocarditis

Myocarditis can lead to autoimmune disease, dilated cardiomyopathy, and heart failure, which is modeled in the mouse by cardiac myosin immunization (experimental autoimmune myocarditis [EAM]). Signal transducer and activator of transcription 3 (STAT3) systemic inhibition exerts both preventive and t...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Avalle, Lidia, Marino, Francesca, Camporeale, Annalisa, Guglielmi, Chiara, Viavattene, Daniele, Bandini, Silvio, Conti, Laura, Cimino, James, Forni, Marco, Zanini, Cristina, Ghigo, Alessandra, Bogorad, Roman L., Cavallo, Federica, Provero, Paolo, Koteliansky, Victor, Poli, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301178/
https://ncbi.nlm.nih.gov/pubmed/32577433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.05.023
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