Low-dose oral cyclophosphamide therapy reduces atherosclerosis progression by decreasing inflammatory cells in a murine model of atherosclerosis

BACKGROUND: Atherosclerosis is a chronic inflammatory disease responsible for most cases of heart disease and stroke in Western countries. The cytotoxic drug cyclophosphamide (CPA) can modulate immune functions, and it has therefore been used to treat patients with autoimmune diseases. Extension of...

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Detalhes bibliográficos
Publicado no:Int J Cardiol Heart Vasc
Main Authors: Sato-Okabayashi, Yayoi, Isoda, Kikuo, Heissig, Beate, Kadoguchi, Tomoyasu, Akita, Koji, Kitamura, Kenichi, Shimada, Kazunori, Hattori, Koichi, Daida, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7300380/
https://ncbi.nlm.nih.gov/pubmed/32577494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcha.2020.100529
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