Lack of IκBNS promotes cholate-containing high-fat diet-induced inflammation and atherogenesis in low-density lipoprotein (LDL) receptor-deficient mice

BACKGROUND: IκBNS, a nuclear IκB protein, regulates a subset of Toll-like receptor (TLR) dependent genes. A cholate-containing high-fat diet (HFD(CA(+))) induces TLR4 mediated early inflammatory response. The present study aims to clarify that the lack of IκBNS promotes atherogenesis in low-density...

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Detalhes bibliográficos
Publicado no:Int J Cardiol Heart Vasc
Main Authors: Kitamura, Kenichi, Isoda, Kikuo, Akita, Koji, Miyosawa, Katsutoshi, Kadoguchi, Tomoyasu, Shimada, Kazunori, Daida, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439265/
https://ncbi.nlm.nih.gov/pubmed/30976650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcha.2019.03.004
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