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An Interleukin-6 Receptor Antibody Suppresses Atherosclerosis in Atherogenic Mice
IκBNS is a nuclear IκB protein which negatively regulates nuclear factor-κB activity. We demonstrated that IκBNS deficiency accelerates atherosclerosis in LDL receptor-deficient (LDLr(−/−)) mice via increased interleukin (IL)-6 production by macrophages. Previous studies showed that the increase in...
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| Publicado no: | Front Cardiovasc Med |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5743912/ https://ncbi.nlm.nih.gov/pubmed/29312959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2017.00084 |
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