Differential effects of high fat diet-induced obesity on oocyte mitochondrial functions in inbred and outbred mice

Maternal obesity can cause reduced oocyte quality and subfertility. Mitochondrial dysfunction plays a central role here, and most often inbred mouse models are used to study these pathways. We hypothesized that the mouse genetic background can influence the impact of high fat diet (HFD)-induced obes...

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Publicado no:Sci Rep
Main Authors: Marei, Waleed F. A., Smits, Anouk, Mohey-Elsaeed, Omnia, Pintelon, Isabel, Ginneberge, Daisy, Bols, Peter E. J., Moerloose, Katrien, Leroy, Jo L. M. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299992/
https://ncbi.nlm.nih.gov/pubmed/32555236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66702-6
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