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Comparing phenotypic variation between inbred and outbred mice

Inbred mice are preferred over outbred mice with the assumption that they display less trait variability. We compared coefficients of variation and failed to find evidence of greater trait stability in inbred mice. We conclude that contrary to conventional wisdom, outbred mice may be better subjects...

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Vydáno v:Nat Methods
Hlavní autoři: Tuttle, Alexander H., Philip, Vivek M., Chesler, Elissa J., Mogil, Jeffrey S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518396/
https://ncbi.nlm.nih.gov/pubmed/30504873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0224-7
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