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Comparing phenotypic variation between inbred and outbred mice

Inbred mice are preferred over outbred mice with the assumption that they display less trait variability. We compared coefficients of variation and failed to find evidence of greater trait stability in inbred mice. We conclude that contrary to conventional wisdom, outbred mice may be better subjects...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Tuttle, Alexander H., Philip, Vivek M., Chesler, Elissa J., Mogil, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518396/
https://ncbi.nlm.nih.gov/pubmed/30504873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0224-7
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