Diversity Outbred Mice at 21: Maintaining Allelic Variation in the Face of Selection

Multi-parent populations (MPPs) capture and maintain the genetic diversity from multiple inbred founder strains to provide a resource for high-resolution genetic mapping through the accumulation of recombination events over many generations. Breeding designs that maintain a large effective populatio...

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Bibliografiske detaljer
Udgivet i:G3 (Bethesda)
Main Authors: Chesler, Elissa J., Gatti, Daniel M., Morgan, Andrew P., Strobel, Marge, Trepanier, Laura, Oberbeck, Denesa, McWeeney, Shannon, Hitzemann, Robert, Ferris, Martin, McMullan, Rachel, Clayshultle, Amelia, Bell, Timothy A., de Villena, Fernando Pardo-Manuel, Churchill, Gary A.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2016
Fag:
Multiparental Populations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144960/
https://ncbi.nlm.nih.gov/pubmed/27694113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.035527
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