Diversity Outbred Mice at 21: Maintaining Allelic Variation in the Face of Selection

Multi-parent populations (MPPs) capture and maintain the genetic diversity from multiple inbred founder strains to provide a resource for high-resolution genetic mapping through the accumulation of recombination events over many generations. Breeding designs that maintain a large effective populatio...

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Détails bibliographiques
Publié dans:G3 (Bethesda)
Auteurs principaux: Chesler, Elissa J., Gatti, Daniel M., Morgan, Andrew P., Strobel, Marge, Trepanier, Laura, Oberbeck, Denesa, McWeeney, Shannon, Hitzemann, Robert, Ferris, Martin, McMullan, Rachel, Clayshultle, Amelia, Bell, Timothy A., de Villena, Fernando Pardo-Manuel, Churchill, Gary A.
Format: Artigo
Langue:Inglês
Publié: Genetics Society of America 2016
Sujets:
Multiparental Populations
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144960/
https://ncbi.nlm.nih.gov/pubmed/27694113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.035527
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