Diversity Outbred Mice at 21: Maintaining Allelic Variation in the Face of Selection

Multi-parent populations (MPPs) capture and maintain the genetic diversity from multiple inbred founder strains to provide a resource for high-resolution genetic mapping through the accumulation of recombination events over many generations. Breeding designs that maintain a large effective populatio...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Chesler, Elissa J., Gatti, Daniel M., Morgan, Andrew P., Strobel, Marge, Trepanier, Laura, Oberbeck, Denesa, McWeeney, Shannon, Hitzemann, Robert, Ferris, Martin, McMullan, Rachel, Clayshultle, Amelia, Bell, Timothy A., de Villena, Fernando Pardo-Manuel, Churchill, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2016
Assuntos:
Multiparental Populations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144960/
https://ncbi.nlm.nih.gov/pubmed/27694113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.035527
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