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Inbred or Outbred? Genetic Diversity in Laboratory Rodent Colonies

Nonmodel rodents are widely used as subjects for both basic and applied biological research, but the genetic diversity of the study individuals is rarely quantified. University-housed colonies tend to be small and subject to founder effects and genetic drift; so they may be highly inbred or show sub...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Brekke, Thomas D., Steele, Katherine A., Mulley, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919727/
https://ncbi.nlm.nih.gov/pubmed/29242387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.300495
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