Circulating tumor DNA analysis to assess risk of progression after long-term response to PD-(L)1 blockade in NSCLC

PURPOSE: Treatment with PD-(L)1 blockade can produce remarkably durable responses in non-small cell lung cancer (NSCLC) patients. However, a significant fraction of long-term responders ultimately progress and predictors of late progression are unknown. We hypothesized that circulating tumor DNA (ct...

Full description

Saved in:
Bibliographic Details
Published in:Clin Cancer Res
Main Authors: Hellmann, Matthew D., Nabet, Barzin Y, Rizvi, Hira, Chaudhuri, Aadel A., Wells, Danny K., Dunphy, Mark, Chabon, Jacob J., Liu, Chih Long, Hui, Angela B., Arbour, Kathryn C, Luo, Jia, Preeshagul, Isabel R., Moding, Everett J., Almanza, Diego, Bonilla, Rene F., Sauter, Jennifer L., Choi, Hyejin, Tenet, Megan, Abu-Akeel, Mohsen, Plodkowski, Andrew J., Johnston, Rocio Perez, Yoo, Christopher, Ko, Ryan B., Stehr, Henning, Gojenola, Linda, Wakelee, Heather A., Padda, Sukhmani K., Neal, Joel W., Chaft, Jamie E., Kris, Mark G., Rudin, Charles M., Merghoub, Taha, Li, Bob T., Alizadeh, Ash, Diehn, Maximilian
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299781/
https://ncbi.nlm.nih.gov/pubmed/32046999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-3418
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items